GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs10935120 | 1 | rs9856693 | chr3:134306913 | ANAPC13 | chr3:134196547-134204865:- | 0.48 | 7.6 | 2.33E-13 | Height |
| BLCA | cis | rs9815354 | 1 | rs9857175 | chr3:41822054 | ULK4 | chr3:41288091-42003660:- | 0.63 | 9.47 | 2.92E-19 | Diastolic blood pressure |
| BLCA | cis | rs1401999 | 1 | rs9858774 | chr3:183652736 | VWA5B2 | chr3:183948317-183960116:+ | -0.24 | -3.84 | 0.000141 | Anterior chamber depth |
| BLCA | cis | rs10935120 | 1 | rs9863786 | chr3:134247203 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.69 | 1.3E-13 | Height |
| BLCA | cis | rs9815354 | 1 | rs9863915 | chr3:41762002 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.9 | 9.78E-21 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs9864217 | chr3:41762206 | ULK4 | chr3:41288091-42003660:- | 0.66 | 9.8 | 2.19E-20 | Diastolic blood pressure |
| BLCA | cis | rs10935120 | 1 | rs9864346 | chr3:134312352 | ANAPC13 | chr3:134196547-134204865:- | 0.48 | 7.6 | 2.33E-13 | Height |
| BLCA | cis | rs10935120 | 1 | rs9864439 | chr3:134298671 | ANAPC13 | chr3:134196547-134204865:- | 0.47 | 7.51 | 4.32E-13 | Height |
| BLCA | cis | rs9815354 | 1 | rs9865127 | chr3:41807448 | ULK4 | chr3:41288091-42003660:- | 0.63 | 9.71 | 4.45E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs9865780 | chr3:41895802 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.91 | 9.53E-21 | Diastolic blood pressure |
| BLCA | cis | rs12638253 | 1 | rs9865905 | chr3:156649594 | LEKR1 | chr3:156544076-156763918:+ | 0.24 | 4.52 | 8.11E-6 | Multiple sclerosis (severity) |
| BLCA | cis | rs9815354 | 1 | rs9866092 | chr3:41895967 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.91 | 9.53E-21 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs9866759 | chr3:41758418 | ULK4 | chr3:41288091-42003660:- | 0.62 | 9.61 | 9.94E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs9867627 | chr3:41795841 | ULK4 | chr3:41288091-42003660:- | -0.6 | -9.14 | 3.72E-18 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs9869207 | chr3:41878661 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.91 | 9.53E-21 | Diastolic blood pressure |